Galen Wright | Drögemöller Lab

Latest

Transcriptome-wide association study uncovers the role of essential genes in anthracycline-induced cardiotoxicity
Integrating disease and drug related phenotypes for improved identification of pharmacogenomic variants
StellarPGx: A nextflow pipeline for calling star alleles in cytochrome P450 genes
A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: A focus on CYP2D6 genotyping
Analyses of adverse drug reactions-nationwide active surveillance network: Canadian Pharmacogenomics Network for Drug Safety database
Genome-Wide Association Studies of drug-induced liver injury make progress beyond the HLA region
Glutaminase deficiency caused by short tandem repeat expansion in GLS
Length of uninterrupted CAG, independent of polyglutamine size, results in increased somatic instability, hastening onset of Huntington Disease
Outcome definition influences the relationship between genetic polymorphisms of ERCC1, ERCC2, SLC22A2 and cisplatin nephrotoxicity in adult testicular cancer patients
Pharmacogenomics of cisplatin-induced ototoxicity: Successes, shortcomings, and future avenues of research
Pharmacogenomics of vincristine-induced peripheral neuropathy implicates pharmacokinetic and inherited neuropathy genes
Further investigation of the role of ACYP2 and WFS1 pharmacogenomic variants in the development of cisplatin-induced ototoxicity in testicular cancer patients
Association between SLC16A5 genetic variation and cisplatin-induced ototoxic effects in adult patients with testicular cancer
The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients
CYP2B6*6 and CYP2B6*18 predict long-term efavirenz exposure measured in hair samples in HIV-positive South African women
Evaluation of predictive CYP2C19 genotyping assays relative to measured phenotype in a South African cohort
Considerations for rare variants in drug metabolism genes and the clinical implications
Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients
Next-generation sequencing of pharmacogenes: a critical analysis focusing on schizophrenia treatment
Characterization of the genetic variation present in CYP3A4 in three South African populations
Introduction of the AmpliChip CYP450 test to a South African cohort: a platform comparative prospective cohort study
Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort
Whole-genome resequencing in pharmacogenomics: moving away from past disparities to globally representative applications
Psychiatric genetics in South Africa: cutting a rough diamond
Pharmacogenomic research in South Africa: Lessons learned and future opportunities in the rainbow nation
Characterization of the genetic profile of CYP2C19 in two South African populations
Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population