Current Perspectives on Data Sharing and Open Science in Pharmacogenomics

Authors

Miao, Deanne Nixie R.

Ladha, Feryal

Lyle, Sarah M.

Olivier, Daniel W.

Ahmed, Samah

Drögemöller, Britt I.

Published

2024

Doi

Abstract

Genome-wide association studies (GWAS) summary statistics provide opportunities to accelerate human genomics research. In pharmacogenomics, assembling large, statistically powerful sample sizes is challenging, emphasizing the vital role of data sharing. To investigate data sharing practices in this field, we reviewed the availability of GWAS summary statistics in 593 pharmacogenomic GWAS articles and found that only 2% contained links to publicly available summary statistics. This highlights the need for improved data sharing initiatives within the pharmacogenomics community.

Citation

Miao, Deanne Nixie R., Ladha, Feryal, Lyle, Sarah M., Olivier, Daniel W., Ahmed, Samah, Drögemöller, Britt I., “Current Perspectives on Data Sharing and Open Science in Pharmacogenomics,” Clinical Pharmacology & Therapeutics 115, 3(2024): 408-411, doi: 10.1002/cpt.3115

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